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GMl-gangliosidosis: Abnormalities in biosynthesis and early processing of β-galactosidase in fibroblasts

✍ Scribed by Eiji Nanba; Akihiko Tsuji; Kiyoshi Omura; Yoshiyuki Suzuki


Book ID
117057832
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
851 KB
Volume
152
Category
Article
ISSN
0006-291X

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Biosynthesis and processing of the protective protein for beta-galactosidase in normal and galactosialidosis fibroblasts were investigated using specific antiserum preparations. A 45-kd precursor was processed to a mature 30-kd protein in normal fibroblasts. The mature protective protein was not det