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GM-CSF cannot substitute for M-CSF in human osteoclastogenesis

✍ Scribed by Jason M. Hodge; Mark A. Kirkland; Geoffrey C. Nicholson


Book ID
116288825
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
370 KB
Volume
321
Category
Article
ISSN
0006-291X

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✍ Jason M. Hodge; Mark A. Kirkland; Geoffrey C. Nicholson πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 304 KB πŸ‘ 1 views

## Abstract Although the critical role of M‐CSF in osteoclastogenesis is well documented, there has been no detailed analysis of how it regulates human osteoclast formation and function in vitro. We used a human osteoclastogenesis model employing CFU‐GM osteoclast precursors cultured for 14 days on