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Glyt-1 expression in cultured human Müller cells and intact retinae

✍ Scribed by Peter Reye; Philip Penfold; David V. Pow

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
217 KB
Volume
34
Category
Article
ISSN
0894-1491

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✦ Synopsis

Abstract

In this study, we demonstrate that Müller cells cultured from human retinas are capable of strongly expressing the glycine transporter Glyt‐1 as assessed by immunocytochemistry. By contrast, intact normal and pathological human retinas exhibit Glyt‐1 immunoreactivity only in neurons. These data suggest that Glyt‐1 expression in cultured Müller cells is an epiphenomenon associated with culturing in vitro, rather than a normal physiological or even pathophysiological phenomenon in vivo. GLIA 34:311–315, 2001. © 2001 Wiley‐Liss, Inc.

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