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Glypican-3 is overexpressed in human hepatocellular carcinoma

โœ Scribed by Young Kwan Sung; Sun Young Hwang; Mi Kyung Park; Mohammad Farooq; In Sook Han; Han Ik Bae; Jung-Chul Kim; Moonkyu Kim

Book ID
108582257
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
604 KB
Volume
94
Category
Article
ISSN
1347-9032

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## Abstract The Glypican (GPC) family is a prototypical member of the cellโ€surface heparan sulfate proteoglycans (HSPGs). The HSPGs have been demonstrated to interact with growth factors, act as coreceptors and modulate growth factor activity. Here we show that based on oligonucleotide array analys

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Osteonectin (ON)/SPARC is a glycoprotein involved in extracellular matrix remodelling. ON expression by myofibroblasts has been reported in fibrotic human liver. As ON also plays a role in cell adhesion, differentiation, and proliferation, this study was designed to document its expression in human