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Glycosylations in the Globular Head of the Hemagglutinin Protein Modulate the Virulence and Antigenic Properties of the H1N1 Influenza Viruses

✍ Scribed by Medina, R. A.; Stertz, S.; Manicassamy, B.; Zimmermann, P.; Sun, X.; Albrecht, R. A.; Uusi-Kerttula, H.; Zagordi, O.; Belshe, R. B.; Frey, S. E.; Tumpey, T. M.; Garcia-Sastre, A.

Book ID: 120454403
Publisher: American Association for the Advancement of Science
Year: 2013
Tongue: English
Weight: 970 KB
Volume: 5
Category: Article
ISSN: 1946-6234
DOI: 10.1126/scitranslmed.3005996

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## Abstract Continued rapid evolution of the influenza A virus is responsible for annual epidemics and occasional pandemics in the Shanghai area. In the present study, the representative strains of A/H1N1 and A/H3N2 influenza viruses isolated in the Shanghai area from 2005 to 2008 were antigenicall