Hepatic glycosphingolipid deficiency and
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Richard Jennemann; Ulrike Rothermel; Shijun Wang; Roger Sandhoff; Sylvia Kaden;
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Article
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2010
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John Wiley and Sons
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English
β 970 KB
Recent studies have reported that glycosphingolipids (GSLs) might be involved in obesityinduced insulin resistance. Those reports suggested that inhibition of GSL biosynthesis in animals ameliorated insulin resistance accompanied by improved glycemic control and decreased liver steatosis in obese mi