Glycose aminoglycane excretion and concentration in the urine of patients with frequently recurrent calcium-oxalate lithiasis prior to and following Diclofenac-Na therapy
✍ Scribed by Brundig, P. ;B�rner, R. -H. ;Haerting, R. ;Janitzky, V. ;Schlichter, A.
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 349 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0300-5623
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✦ Synopsis
Excretion and concentration of glycose aminoglycans were measured in 19 patients with frequent relapses of calcium-oxalate lithiasis, prior to and two weeks after onset of Diclofenac-Na therapy. In most patients, markedly enhanced glycose aminoglycan concentration and excretion could be demonstrated. Elevation of the high-molecular inhibitor potential in the urine results in reduced risk of calcium-oxalate lithogenesis, which may explain the therapeutic success of nonsteroidal anti-inflammatory drugs in the treatment of therapy resistant calcium-oxalate lithiasis.