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Glycosaminoglycan mimetics–induced mobilization of hematopoietic progenitors and stem cells into mouse peripheral blood: Structure/function insights

✍ Scribed by Patricia Albanese; Danielle Caruelle; Guilhem Frescaline; Jean Delbé; Laurence Petit-Cocault; Eric Huet; Nathalie Charnaux; Georges Uzan; Dulce Papy-Garcia; José Courty


Book ID
113616620
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
739 KB
Volume
37
Category
Article
ISSN
0301-472X

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## Abstract The immune system of vertebrates detects bacterial DNA as a “danger signal” based on the presence of unmethylated CpG motifs. We examined whether oligodeoxynucleotides (ODNs) with CpG motifs (CpG‐ODNs) also induce mobilization of hematopoietic progenitor cells (HPCs). Mice challenged wi