Glycolipides des nocardiae. Isolement et caractérisation de mononocardomycolates et de dinocardomycolates de tréhalose dans Nocardia caviae

✍ Scribed by M.T. Pommier; G. Michel

• Book ID: 103036939
• Publisher: Elsevier Science
• Year: 1979
• Tongue: English
• Weight: 334 KB
• Volume: 24
• Category: Article
• ISSN: 0009-3084
• DOI: 10.1016/0009-3084(79)90084-7

✦ Synopsis

Two groups of glycolipids have been isolated from a strain of Nocardia caviae and their structures have been determined. These glycolipids are trehalose 6-mononocardonaycolates and trehalose 6,6'-dinocardomycolatcs (cord-factors). In the trehalose monoesters mono and diunsaturated nocardomycolic acids with 52 to 58 carbon atoms have been found while in the trehalose diesters only diunsaturated nocardomycolic acids with 54, 56 and 58 carbon atoms have been found. These glycolipids arc the first cord-factors with true nocardomycolic acids isolated from Nocardiae.

Deux groupes de glycolipides out dt& isol,Ss d'une souche de Nocardia caviae et la structure de ces glycolipides a 6t6 ddtermint~e. II s'agit de 6-mononocardomycolates de trdhalose et de 6,6'-dinocardomycolates de trt~halose (cord-factors). Dans les monoesters de trdhalose les acides nocardomycoliques sont des acidcs mono et di6thyl6niqucs ayant de 52 ;l 58 atomes de carbone. Les diesters de tr6halose renfcrment seu[ement des aeides nocardomyeoliques di6th) [-6niques avcc 54, 56 et 58 atomes de carbone. ('es g[ycolipides sont les premiers cord-factors z) acides m)cardomycoliques isol6s de Nocardiae.