✦ LIBER ✦
Glycogen storage disease Type I. Results of treatment with frequent daytime feeding, combined with nocturnal intragastric feeding and with administration of anα-glucosidase inhibitor
✍ Scribed by H. Gröbe; K. Ullrich
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 265 KB
- Volume
- 140
- Category
- Article
- ISSN
- 0340-6997
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✦ Synopsis
Seven patients with glycogen disease type I have been treated with nocturnal intragastric feeding combined with frequent daytime feeding. Follow-up shows a striking improvement in their clinical condition including growth rate. Determination of biochemical parameters reveals a significant increase in mean blood glucose levels and a significant decrease of lactate, pyruvate, alanine, uric acid, triglycerides, and SGOT in blood. Additional administration of an a-glucosidase inhibitor in four patients caused a significant increase in blood lactate despite unchanged blood glucose levels.