Glycoconjugate expression during embryogenesis and its biological significance
β Scribed by Bruce A. Fenderson; E. M. Eddy; Sen-Itiroh Hakomori
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 877 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0265-9247
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Many stageβspecific embryonic antigens (SSEAs) have been identified as glycoconjugates. These molecules may play diverse roles in the development of the embryo, including regulation of cell growth, recognition, and differentiation. The example of SSEAβ1 is described in detail. This molecule appears to play an essential role in compaction of the early mouse embryo, and may illustrate the general importance of carbohydrateβcarbohydrate interactions in controlling cell surface interactions in development.
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