Glyco-SeS: Selenenylsulfide-Mediated Protein Glycoconjugation—A New Strategy in Post-Translational Modification

✍ Scribed by David P. Gamblin; Philippe Garnier; Sander van Kasteren; Neil J. Oldham; Antony J. Fairbanks; Benjamin G. Davis

• Book ID: 101560263
• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 354 KB
• Volume: 43
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.200352975

✦ Synopsis

Precise mimics of post-translationally modified proteins can be constructed by using a highly selective, selenenylsulfide-mediated method. On the following pages B. G. Davis and co-workers describe the use of this approach for the glycosylation of a protein with a heptasaccharide glycan and for a multiple site-selective, chemical protein glycosylation.