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Glycine protects against hepatocyte killing by KCN or hypoxia by preventing intracellular Na+ overload in the rat

โœ Scribed by R Carini; G Bellomo; M De Cesaris; E Albano


Book ID
118686647
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
255 KB
Volume
26
Category
Article
ISSN
0270-9139

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Glycine protects against hepatocyte kill
โœ R Carini; G Bellomo; M De Cesaris; E Albano ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 253 KB

Glycine has been shown to prevent hepatocyte death induced by anoxia and by several toxic agents. However, the mechanisms responsible for such a cytoprotective effect have not yet been entirely clarified. We have previously shown that an uncontrolled increase in intracellular Na+ is critical for hep