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Glycine conjugation of para-aminobenzoic acid (PABA) as a quantitative test for liver function

✍ Scribed by Z. Verjee; K. Furuya; E. Roberts; L. Yung-Jato; L. Ellis; E. Giesbrecht; P. Durie

Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 241 KB
Volume: 27
Category: Article
ISSN: 0009-9120
DOI: 10.1016/0009-9120(94)90143-0

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Objectives: Our hypothesis is that because of its hepatic metabolism paraaminobenzoic acid (PABA) could be a test of liver function. ## Design and methods: PABA is well absorbed by the gastrointestinal tract and acetylated and conjugated in the liver to glycine before being excreted. Its three ma