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Glycerine injection and crystal formation in the larynx: A negative study

✍ Scribed by Martin Klabacha; Akram Farag; Cesar Reyes; Robert Lewy; Robert Borkenhagen

Book ID
102435767
Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
266 KB
Volume
16
Category
Article
ISSN
0022-4790

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✦ Synopsis

Abstract

Glycerine as a vehicle may be injected alone or with Teflon to reposition a lateral lying paralyzed vocal cord. During the study of a particular patient, crystal formation was observed in laryngeal tissues injected with glycerine. It was hypothesized that glycerine metabolized to oxalic acid crystals via the glyoxylic acid pathway.

To confirm this proposition, the gluteus muscle of guinea pigs was injected with glycerine, and at weekly intervals submitted for ordinary and polarized light microscopic examination. The formation of crystals after glycerine injection was not found in the guinea pig. Similarly, no foreign material or crystals were found after centrifuging the stored glycerine.

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Office-based injection laryngoplasty in
Office-based injection laryngoplasty in the irradiated larynx
✍ Yamilet Tirado; Jan S. Lewin; Katherine A. Hutcheson; Michael E. Kupferman πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 775 KB

## Abstract ## Objectives/Hypothesis: To review the clinical results of office‐based injection laryngoplasty with two different therapeutic materials in patients with vocal fold paralysis and history of radiation therapy to the larynx. ## Study Design: Retrospective study. ## Methods: Chart re