𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Glycemic risk factors of diabetic vascular complications: the role of glycemic variability

✍ Scribed by Francesco Zaccardi; Dario Pitocco; Giovanni Ghirlanda

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
262 KB
Volume
25
Category
Article
ISSN
1520-7552

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Achieving adequate targets relatively to all risk factors is considered a standard of care for patients with diabetes mellitus. To date, current guidelines underline the importance of the ‘glucose triad’ (post‐prandial glucose, fasting plasma glucose and glycated haemoglobin) as the three glycemic factors that should be controlled in diabetes care; however, several literature data show that optimizing glycemic control needs achieving a control of glycemic variations. The objective of the present work is reviewing biological and clinical data supporting the role of glycemic variability, its measurement and relationship with the three other well‐known glycemic risk factors and evidencing the areas that need further investigation. At last, we propose a simple model that summarizes the ‘glucose triad’ plus the ‘new’ risk factor glycemic variability (the ‘Pyramid of the Risk’). Copyright © 2009 John Wiley & Sons, Ltd.

📜 SIMILAR VOLUMES

Dietary carbohydrates and breast cancer
Dietary carbohydrates and breast cancer risk: A prospective study of the roles of overall glycemic index and glycemic load
✍ Stephanie A. Navarro Silvera; Meera Jain; Geoffrey R. Howe; Anthony B. Miller; T 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 90 KB 👁 2 views

## Abstract We examined breast cancer risk in association with overall glycemic index (GI), glycemic load (GL), and dietary carbohydrate and sugar intake in a prospective cohort of 49,613 Canadian women enrolled in the National Breast Screening Study who completed a self‐administered food frequency

The role of vascular risk factors in lat
The role of vascular risk factors in late onset bipolar disorder
✍ Hari Subramaniam; Michael S. Dennis; E. Jane Byrne 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB

## Abstract ## Background The association between late life depression and cerebro‐vascular risk and cerebro‐vascular disease is well established. Do similar links exist with late onset bipolar disorder? ## Aims and Objectives Patients with early onset (less than 60 years of age) bipolar disorde

Role of the hypoxia sensing system, acid
Role of the hypoxia sensing system, acidity and reproductive hormones in the variability of vascular endothelial growth factor induction in human breast carcinoma cell lines
✍ Prudence A. E. Scott; Jonathan M. Gleadle; Roy Bicknell; Adrian L. Harris 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 131 KB 👁 3 views

Vascular endothelial growth factor (VEGF) is a potent angiogenic factor implicated in many pathological processes. We investigated the regulation of 4 alternatively spliced isoforms (121, 165, 189 and 206 amino acids) by hypoxia, hypoglycemia, acidity, female reproductive hormones and vitamin D in b