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Glycated albumin activates NADPH oxidase in rat mesangial cells through up-regulation of p47phox

✍ Scribed by Yanzhang Li; Shuxia Wang


Book ID
116300214
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
693 KB
Volume
397
Category
Article
ISSN
0006-291X

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## Abstract ## Background Hyperglycaemia induces non‐enzymatic glycation reactions in proteins which generate Amadori products and advanced glycation end‐products; the latter are thought to participate in the vascular complications of diabetic patients. However, the exact mechanisms concerning the