Gly Scan of Prouroguanylin to Investigate Essential Amino Acid Residues for the Intra-Molecular Chaperone Function

Identification of single amino acid resi

Identification of single amino acid residues essential for the binding of lipopolysaccharide (LPS) to LPS binding protein (LBP) residues 86–99 by using an Ala-scanning library

✍ Dr O. Reyes; M. G. Vallespi; H. E. Garay; L. J. Cruz; L. J. González; G. Chinea; 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 112 KB

## Abstract Lipopolysaccharide binding protein (LBP) is a 60 kDa acute phase glycoprotein capable of binding to LPS of Gram‐negative bacteria and facilitating its interaction with cellular receptors. This process is thought to be of great importance in systemic inflammatory reactions such as septic