GlutathioneS-transferase M1, T1, and P1 gene polymorphisms and carotid atherosclerosis in Korean patients with rheumatoid arthritis
β Scribed by Jae-Hong Park; Ahmed El-Sohemy; MarilynC. Cornelis; Hyun-Ah Kim; Shin-Yoon Kim; Sang-Cheol Bae
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 205 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0172-8172
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## Abstract ## Objective Glutathione Sβtransferase (GST) genes as well as heme oxygenase 1 gene (HMOX1) encode enzymes that detoxify carcinogens and protect against oxidative stress. This study was undertaken to examine the impact of geneβsmoking interactions on susceptibility to rheumatoid arthri
## Abstract ## Objective To determine whether the relationship between smoking and disease severity in women with rheumatoid arthritis (RA) is associated with polymorphism at the glutathione Sβtransferase (GST) M1 locus. ## Methods Genotyping for GSTM1 was carried out using polymerase chain reac