Characterization of metformin transport
β
Naim A. Khan; Nicolas Wiernsperger; Veronique Quemener; RenΓ© Havouis; Jacques P.
π
Article
π
1992
π
John Wiley and Sons
π
English
β 686 KB
## Abstract The biochemical properties of the metformin transport system were studied in NIH 3T3 cells. ^14^Cβmetformin uptake appeared to be a sodium dependent process. Isoβosmotical replacement of Na^+^ by choline chloride in the assay medium resulted in a decrease of metformin uptake. Amiloride