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Glutathione S-transferase-π expression and glutathione concentration in ovarian carcinoma before and after chemotherapy

✍ Scribed by Xiusi Cheng; Junzo Kigawa; Yukihisa Minagawa; Yasunobu Kanamori; Hiroaki Itamochi; Makoto Okada; Naoki Terakawa


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
145 KB
Volume
79
Category
Article
ISSN
0008-543X

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✦ Synopsis


BACKGROUND.

To clarify the role of glutathione (GSH) in the chemotherapy resis-Xiusi Cheng, M


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## BACKGROUND. Resistance to chemotherapy agents is a major problem in the treatment of patients with nonsmall cell lung carcinoma (NSCLC). Recent studies have indicated that glutathione S-transferase-n (GST-n) may play an important role in the resistance of cancer cells to alkylating agents, inclu