## Abstract Glutathione S‐transferases (GSTs) are involved in detoxification of carcinogens, __e.g__., from tobacco smoke. Therefore, polymorphisms in the GST genes have been considered as potential modifiers of individual cancer risk. In a population‐based case‐cohort study where cases and the sub
✦ LIBER ✦
Glutathione S-transferase T1-null genotype interacts synergistically with heavy smoking on lung cancer risk
✍ Scribed by Sai-Mei Hou; Susann Fält; Fredrik Nyberg
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 59 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0893-6692
- DOI
- 10.1002/em.1054
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## Abstract ## Objective Glutathione S‐transferase (GST) genes as well as heme oxygenase 1 gene (HMOX1) encode enzymes that detoxify carcinogens and protect against oxidative stress. This study was undertaken to examine the impact of gene–smoking interactions on susceptibility to rheumatoid arthri