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Glutathione S-transferase M1 and T1 and cytochrome P4501A1 polymorphisms in relation to the risk for benign and malignant head and neck lesions

✍ Scribed by Michael B. Oude Ophuis; Esther M. M. van Lieshout; Hennie M. J. Roelofs; Wilbert H. M. Peters; Johannes J. Manni

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 190 KB
Volume: 82
Category: Article
ISSN: 0008-543X
DOI: 10.1002/(sici)1097-0142(19980301)82:5<936::aid-cncr20>3.0.co;2-0

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✦ Synopsis

GSTs). Genetic variability in CYP and GST isoenzymes may

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✍ Brendan T. Keenan; Lori B. Chibnik; Jing Cui; Bo Ding; Leonid Padyukov; Henrik K 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 109 KB 👁 1 views

## Abstract ## Objective Glutathione S‐transferase (GST) genes as well as heme oxygenase 1 gene (HMOX1) encode enzymes that detoxify carcinogens and protect against oxidative stress. This study was undertaken to examine the impact of gene–smoking interactions on susceptibility to rheumatoid arthri