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Glutathione S-transferase and cytochrome-P-450 polymorphism as risk factors for squamous cell carcinoma of the larynx

โœ Scribed by Volker Jahnke; Christoph Matthias; Antony Fryer; Richard Strange


Book ID
117026136
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
391 KB
Volume
172
Category
Article
ISSN
0002-9610

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Differences in genetic susceptibility to tobacco-induced carcinogenesis appear to modulate an individual's risk of squamous-cell carcinoma of the head and neck (SCCHN). Risk for SCCHN may be associated with the null alleles of the carcinogen-metabolizing genes glutathione-S-transferase (GST) T1 and