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Glutathione peroxidase activity is neuroprotective in models of Huntington's disease

✍ Scribed by Mason, Robert P; Casu, Massimiliano; Butler, Nicola; Breda, Carlo; Campesan, Susanna; Clapp, Jannine; Green, Edward W; Dhulkhed, Devyani; Kyriacou, Charalambos P; Giorgini, Flaviano


Book ID
120991254
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
826 KB
Volume
45
Category
Article
ISSN
1061-4036

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We studied whether combinations of botanical extracts enriched in either D 9 -tetrahydrocannabinol (D 9 -THC) or cannabidiol (CBD), which are the main constituents of the cannabis-based medicine Sativex, provide neuroprotection in rat models of Huntington's disease (HD). We used rats intoxicated wit