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Glutathione Peroxidase-1 and -2 Protect Mice from Salmonella-Induced Colitis

✍ Scribed by Steven Esworthy, Robert; Kim, Byung-Wook; Doroshow, James H; Leto, Thomas L; Chu, Fong-Fong

Book ID
122507318
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
209 KB
Volume
53
Category
Article
ISSN
0891-5849

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## Abstract The enzyme glutathione peroxidase 1 (GPx1) is involved in the cellular detoxification of peroxides. To test for the consequences of GPx deficiency in astrocytes, astrocyte‐rich primary cultures from wild‐type and GPx1‐deficient [GPx1(–/–)] mice were exposed to H~2~O~2~. In GPx1(–/–) ast