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Glutathione monoethyl ester protects against glutathione deficiencies due to aging and acetaminophen in mice

โœ Scribed by Theresa S Chen; John P Richie Jr.; Herbert T Nagasawa; Calvin A Lang


Book ID
114095956
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
238 KB
Volume
120
Category
Article
ISSN
0047-6374

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L-2-oxothiazolidine-4-carboxylic acid (OTC) is a cysteine prodrug that maintains glutathione in tissues. Here, its effect on alcohol-induced liver injury in an enteral alcohol feeding model was investigated. Male Wistar rats were given control high-fat or ethanol containing diets enterally for 4 wee