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Glutathione depletion modulates methanol, formaldehyde and formate toxicity in cultured rat conceptuses

โœ Scribed by C. Harris; M. Dixon; J.M. Hansen


Book ID
111576519
Publisher
Springer
Year
2004
Tongue
English
Weight
253 KB
Volume
20
Category
Article
ISSN
0742-2091

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Methanol, formaldehyde, and sodium forma
โœ Jason M. Hansen; Kristi M. Contreras; Craig Harris ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 312 KB ๐Ÿ‘ 2 views

BACKGROUND: Methanol (CH 3 OH) is believed to be teratogenic based on rodent studies. The mouse is more sensitive than the rat, but mechanisms of toxicity and identification of teratogenic metabolites are uncertain. METHODS: Rat and mouse whole embryo cultures are used to distinguish toxicity of CH