✦ LIBER ✦

Glutathione depletion causes cell growth inhibition and enhanced apoptosis in pancreatic cancer cells

✍ Scribed by Thomas Schnelldorfer; Susanne Gansauge; Frank Gansauge; Sophia Schlosser; Hans G. Beger; Andreas K. Nussler

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 139 KB
Volume: 89
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(20001001)89:7<1440::aid-cncr5>3.0.co;2-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Actinomycin D induces apoptosis and inhi

Actinomycin D induces apoptosis and inhibits growth of pancreatic cancer cells

✍ Jörg Kleeff; Marko Kornmann; Harneet Sawhney; Murray Korc 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 366 KB 👁 1 views

Pancreatic cancer cells are usually resistant to apoptosis induced by cytotoxic drugs, by activation of surface receptors such as Fas and TNF receptor or by serum or growth factor withdrawal. Actinomycin D (actD) is an inhibitor of RNA synthesis and acts as a potent inducer of apoptosis in several c

CD154 inhibits tumor-induced apoptosis i

CD154 inhibits tumor-induced apoptosis in dendritic cells and tumor growth

✍ Clemens Esche; Andrea Gambotto; Yuji Satoh; Valentin Gerein; Paul D. Robbins; Si 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 372 KB 👁 2 views

Medroxyprogesterone acetate inhibits hum

Medroxyprogesterone acetate inhibits human pancreatic carcinoma cell growth by inducing apoptosis in association with Bcl-2 phosphorylation

✍ Michio Abe; Jun-ichi Yamashita; Michio Ogawa 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 377 KB 👁 1 views

## BACKGROUND. A previous study found that medroxyprogesterone acetate (MPA) delayed the in vivo growth of three (AsPC-1, Capan-2, and MiaPaCa-2) of nine human pancreatic carcinoma cell lines transplanted into nude mice (Cancer 1995; 75:1263-72). The current study was undertaken to evaluate the bas

The cAMP analog 8-Cl-cAMP inhibits growt

The cAMP analog 8-Cl-cAMP inhibits growth and induces differentiation and apoptosis in retinoblastoma cells

✍ Gianfranco Fassina; Maria Grazia Aluigi; Susan Gentleman; Paul Wong; Tania Cai; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 209 KB 👁 2 views

Retinoblastomas appear to be derived from a multipotential stem cell of the retina, due to alterations of the Rb1 gene. These tumors arise only within a discrete time frame during childhood, prior to terminal differentiation of the retinal precursor cells. Treatment of retinoblastoma cells with cert

Racial differences in prostate cancer gr

Racial differences in prostate cancer growth: Apoptosis and cell proliferation in Caucasian and African-American patients

✍ Guo, Yanping; Sigman, David B.; Borkowski, Andrew; Kyprianou, Natasha 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 219 KB 👁 1 views

Epidemiologic evidence reveals striking racial differences in incidence and clinical behavior of prostate cancer among American men. In this study, we assessed the incidence of apoptosis and cell proliferation in prostate cancer specimens from African-American and Caucasian patients in an attempt to

Potent inhibition of cell density-depend

Potent inhibition of cell density-dependent apoptosis and enhancement of survival by dimethyl sulfoxide in human myeloblastic HL-60 cells

✍ Yoko Nishizawa; Kumiko Saeki; Hisamaru Hirai; Yoshio Yazaki; Fumimaro Takaku; Ak 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 261 KB

Human myeloblastic cell line HL-60 cells undergo apoptosis during in vitro culture in a cell density-dependent manner, and this cell density-dependent apoptosis was observed when the concentration of cultured cells exceeded 8-10 x 10(5) cells/ml. Dimethyl sulfoxide (DMSO), a differentiation inducer