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Glutathione depletion and increased apoptosis rate in human cystinotic proximal tubular cells

✍ Scribed by Guido F. Laube; Vanita Shah; Victoria C. Stewart; Iain P. Hargreaves; Mushfequr R. Haq; Simon J. R. Heales; William G. van’t Hoff


Book ID
106160169
Publisher
Springer
Year
2006
Tongue
English
Weight
132 KB
Volume
21
Category
Article
ISSN
0931-041X

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## Abstract Present study investigated whether endosulfan, an organochlorine pesticide is able to deplete glutathione (GSH) and induce apoptosis in human peripheral blood mononuclear cells (PBMC) in vitro. The role of oxidative stress in the induction of apoptosis was also evaluated by the measurem