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Glutathione conjugation in the isolated perfused rabbit lung: the effects of carbon monoxide, buthionine sulfoximine and cibacron blue

✍ Scribed by Yang, C.Mierha; Carlson, Gary P.

Book ID
122594735
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
508 KB
Volume
52
Category
Article
ISSN
0378-4274

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## Abstract Glutathione (GSH) has often been implicated in the mechanism of resistance to platinum anti‐cancer drugs. It has been suggested that GSH may reduce the cytotoxicity of these drugs by forming inactive conjugates and by enhancing the repair of DNA‐platinum crosslinks. In the present study