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Glutathione conjugation as a bioactivation reaction

โœ Scribed by Peter J van Bladeren

Book ID
114008603
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
146 KB
Volume
129
Category
Article
ISSN
0009-2797

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The elimination and metabolism of [14-C]-tetrachloroethylene (Tetra) was studied in female rats and mice after the oral administration of 800 mg/kg [14-C]-Tetra. Elimination of unchanged Tetra was the main pathway of elimination in both species and amounted to 91.2% of the dose in rats and 85.1% in