Glutarimide nucleosides synthesis and properties of analogs of 1-deaza-thymidine
β Scribed by M.J. Wanner; G.J. Koomen
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 221 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Dedicated to Dieter Seebach on the occasion of his 65th birthday In the context of broadening the knowledge on substrate specificity of Herpes simplex virus type 1 thymidine kinase (HSV-1 TK) and Varicella-Zoster virus thymidine kinase (VZV TK), new derivatives of 9-(2hydroxypropyl)-substituted
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The protected ethidium nucleosides 8-(3%,5%-di-O-benzoyl-2%-deoxy-D-ribofuranosyl)-3-acetamido-5-ethyl-6-phenylphenanthridinium (5), 8-(3%,5%-di-O-acetyl-2%-deoxy-D-ribofuranosyl)-3-acetamido-5-ethyl-6-phenyl-phenanthridinium (6), and the acyclic analog 8-[(3R)-1,3-dihydroxy-4-yl]-acetamido-3-amino-
5-Heteroarylthymine analogs (5) were synthesized via binucleophilic attack with bidentate thiols on the cyano group of cyanoacetylurea to form the heteroarylurea derivatives (2-4) followed by their cyclization with formamide. Also, their nucleosides 6a and 6b with 2,3,4,6-tetra-O-acetyl-β£-D-glucopyr