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Glutarimide antibiotics part VIII : A stereoselective synthesis of dl-α-epi-isocycloheximide

✍ Scribed by Francis Johnson; A.A. Carlson


Publisher
Elsevier Science
Year
1965
Tongue
French
Weight
173 KB
Volume
6
Category
Article
ISSN
0040-4039

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✦ Synopsis


Successful synthetic approaches to cycloheximide (I) and its isomers have led either to I itself', to neocycloheximide l,o (II) or to mixtures of isocycloheximide (III) andd-e&-isocycloheximide (IV) together with other position isomers4. The latter in ?H CH3.$.


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Cyclopentanones: VIII A stereoselective
✍ F. Van Hulle; V. Sipido; M. Vandewalle 📂 Article 📅 1973 🏛 Elsevier Science 🌐 French ⚖ 177 KB

A previous paper' described the potentiality of 3-alkyl-1,2,4-cyclopentanetriones (in the mono enol form I) as starting materials for the synthesis of the prostaglandin skeleton. In this communication we wish to report the synthesis