Glutamine synthetase (GS) has been qualified as a very specific marker of astroglial-type neuroglia in vertebrate neural tissues. In this paper we have begun to examine the possibility that glial localization of GS could be a ubiquitous characteristic of complex nervous systems. To this end we have
Glutamine synthetase immunoreactivity is present in oligodendroglia of various regions of the central nervous system
β Scribed by Fernando D'Amelio; Lawrence F. Eng; Michael A. Gibbs
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 1019 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0894-1491
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β¦ Synopsis
Abstract
Glutamine synthetase immunoreactive oligodendrocytes were identified in the cerebral cortex, cerebellum, brain stem, and spinal cord. They were mostly confined to the gray matter, particularly close to neurons and processes. The white matter showed few immunoreactive oligodendroglia. It was suggested that some type of oligodendrocytes, specially those in perineuronal location, might fulfill a functional role more akin to astrocytes than to the normally myelinating oligodendroglia.
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