Glutamine synthetase activities in spinal white and gray matter 7 days following spinal cord injury in rats
โ Scribed by Richard L Benton; C.David Ross; Kenneth E Miller
- Book ID
- 117471019
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 189 KB
- Volume
- 291
- Category
- Article
- ISSN
- 0304-3940
No coin nor oath required. For personal study only.
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## Abstract Spinal cord injury (SCI) involves the loss of neurons and glia due to initial mechanical and secondary biochemical mechanisms. Treatment with the sodium channel blocker tetrodotoxin (TTX) reduces acute white matter pathology and increases both axon density and hindlimb function chronica
Longitudinal in vivo magnetic resonance imaging (MRI) of moderately injured rat spinal cord was performed to investigate the transient loss in gray matter (GM) and white matter (WM) contrast. In addition, neurobehavioral scores (based on open field walking, inclined plane test, and grid walking) and