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Glutamine in the pathogenesis of acute hepatic encephalopathy

✍ Scribed by Kakulavarapu V. Rama Rao; Arumugam R. Jayakumar; Michael D. Norenberg


Book ID
116765809
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
356 KB
Volume
61
Category
Article
ISSN
0197-0186

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## Abstract Hepatic encephalopathy (HE) results from acute or chronic liver dysfunction and is associated with hyperammonemia. Ammonium ions penetrate from blood to brain, where they form glutamine (Gln) in the reaction with glutamate catalyzed by an astroglia‐specific enzyme, glutamine synthetase