Glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) enzyme activities in different tissues of Sarotherodon mossambicus (Peters) exposed to a carbamate pesticide, carbaryl
✍ Scribed by Ramaswamy, Murugesan; Thangavel, Palaniswamy; Panneer Selvam, N
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 81 KB
- Volume
- 55
- Category
- Article
- ISSN
- 1526-498X
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✦ Synopsis
The activity levels of glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) enzymes were estimated in liver, muscle and brain tissues of the ®sh, Sarotherodon mossambicus (Peters), which had been exposed to sub-lethal (3 mg litre À1 ) and lethal (25 mg litre À1 ) concentrations of the carbamate insecticide carbaryl. Based on the results obtained, the changes in GOT and GPT levels in liver, muscle and brain following different periods of sub-lethal and lethal carbaryl exposures suggested that S mossambicus showed adaptive elevation in the activity levels of the two aminotransferase enzymes in the tissues, thereby probably aiding gluconeogenesis through transamination of glucogenic amino acids to meet the energy demand under carbaryl toxicity.