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Glutamic acid decarboxylase expression in islets and brain

✍ Scribed by Giorda, Roberto; Peakman, Mark; Tan, K.C.; Vergani, Diego; Trucco, Massimo

Book ID
122517788
Publisher
The Lancet
Year
1991
Tongue
English
Weight
343 KB
Volume
338
Category
Article
ISSN
0140-6736

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## Abstract The ketogenic diet is a very low‐carbohydrate, high‐fat diet used to treat refractory epilepsy. We hypothesized that this diet may act by increasing expression of glutamic acid decarboxylase (GAD), the rate‐limiting enzyme in γ‐aminobutyric acid (GABA) synthesis. Thus, we evaluated brai