## Abstract The termination of chemical neurotransmission in the CNS involves the rapid removal of neurotransmitter from synapses by specific transport systems. Such mechanism operates for the three major amino acid neurotransmitters glutamate, Ξ³βaminobutyric acid (GABA) and glycine. To date, five
β¦ LIBER β¦
Glutamate transporters in hyperammonemia
β Scribed by Roger F. Butterworth
- Book ID
- 117409784
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 94 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0197-0186
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Abnormalities in glutamate metabolism and glutamatergic neurotransmission appear to play a major role in the pathogenesis of hyperammonemia and hepatic encephalopathy. Astrocytes may be involved in these derangements as ammonia has been shown to impair the ability of these cells to take up glutamate