Glutamate toxicity enhances tau gene exp
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FranΓ§oise Esclaire; Mathieu Lesort; Cecile Blanchard; Jacques Hugon
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Article
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1997
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John Wiley and Sons
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English
β 268 KB
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Tau protein is a microtubule-associated protein normally expressed in neurons. In Alzheimer's disease (AD) brains, phosphorylated tau accumulates in paired helical filaments which form neurofibrillary tangles in affected neurons; moreover, tau mRNA expression is increased in affected regions of AD b