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Glutamate decarboxylase (GAD65) gene expression is increased by dopamine receptor agonists in a subpopulation of rat striatal neurons

โœ Scribed by Nathalie Laprade; Jean-Jacques Soghomonian

Book ID
117386886
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
778 KB
Volume
48
Category
Article
ISSN
0169-328X

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Glutamate decarboxylase (GAD67 and GAD65
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The cellular distribution of the mRNAs encoding for the two isoforms of glutamate decarboxylase, GAD67 and GAD65, was analyzed by in situ hybridization histochemistry in the caudate nucleus and putamen of control and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated parkinsonian squirrel m

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The levels of mRNAs encoding for the two isoforms of glutamate decarboxylase, GAD65 and GAD67, were measured in subpopulations of striatal neurons in adult rats depleted of dopamine as neonates with 6-OHDA and chronically injected with vehicle or with the dopamine receptor agonists apomorphine or SK