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Glucuronide conjugation reduces the cytotoxicity but not the mutagenicity of benzo(a)pyrene in the CHO/HGPRT assay

โœ Scribed by Leslie Recio; Abraham W. Hsie

Book ID
112213184
Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
780 KB
Volume
4
Category
Article
ISSN
0270-3211

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โœ Demarini, David M. ;Brimer, Patricia A. ;Hsie, Abraham W. ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Wiley (John Wiley & Sons) โš– 637 KB

We used the Chinese hamster ovary cell/hypoxanthine-guanine phosphoribosyl-transferase (CHO/HGPRT) assay to determine the cytotoxicity and mutagenicity of a crude coal oil, the neutral fraction of this crude, and the following three subfractions of the neutral fraction: aliphatic, neutral polar, and