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Glucuronidation of oxazepam and paracetamol in severe hypothyroidism

✍ Scribed by J. Sonne; S. Boesgaard; H.E. Poulsen; S. Loft; J. Mølholm Hansen; M. Døssing; F. Andreasen

Book ID
115883784
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
247 KB
Volume
183
Category
Article
ISSN
0014-2999

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Glucuronidation of oxazepam is not spare
Glucuronidation of oxazepam is not spared in patients with hepatic encephalopathy
✍ Jesper Sonne; Per Buch Andreasen; Steffen Loft; Martin Døsing; Frederik Andrease 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 621 KB

The disposition of oral oxazepam was investigated in seven patients with decompensated cirrhosis and encephalopathy and in nine healthy individuals to further examine the hypothesis of preservation of glucuronidation in liver disease. The patients showed a severe reduction in the quantitative liver