The polyol pathway and glucose 6-phospha
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M. Lorenzi; S. Toledo; G. R. Boss; M. J. Lane; D. F. Montisano
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Article
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1987
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Springer
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English
โ 704 KB
In an attempt to identify the mechanisms underlying the ill effects of high glucose previously described in cultured human endothelial cells, we have investigated in these cells the activity of the polyol pathway and accumulation of glucose 6-phosphate, a powerful agent of non-enzymatic glycosylatio