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Glucose transporter isoform (GLUT) 2 expression in beta-cells of long-term syngeneic islet grafts

✍ Scribed by K. D. Kohnert; F. Wohlrab; H. J. Hahn; L. Cossel


Publisher
Springer
Year
1997
Tongue
English
Weight
383 KB
Volume
34
Category
Article
ISSN
0940-5429

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The purpose of these experiments was to test the hypothesis that impaired glucose-stimulated insulin secretion in NIDDM is due to mutations in the islet beta cell/liver glucose transporter (GLUT 2) gene. Using oligonucleotide primers flanking each of the 11 exons, the structural portion of the gene