Variability of the pancreatic islet beta
✍
Y. Tanizawa; A. C. Riggs; K. C. Chiu; R. C. Janssen; D. S. H. Bell; R. P. C. Go;
📂
Article
📅
1994
🏛
Springer
🌐
English
⚖ 945 KB
The purpose of these experiments was to test the hypothesis that impaired glucose-stimulated insulin secretion in NIDDM is due to mutations in the islet beta cell/liver glucose transporter (GLUT 2) gene. Using oligonucleotide primers flanking each of the 11 exons, the structural portion of the gene