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Glucose requirement for hypoxic accumulation of hypoxia-inducible factor-1α (HIF-1α)

✍ Scribed by Dirk Vordermark; Peter Kraft; Astrid Katzer; Tobias Bölling; Jochen Willner; Michael Flentje


Book ID
116333554
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
514 KB
Volume
230
Category
Article
ISSN
0304-3835

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## Abstract Quercetin, a ubiquitous bioactive plant flavonoid, has been shown to inhibit the proliferation of cancer cells and induce the accumulation of hypoxia‐inducible factor‐1α (HIF‐1α) in normoxia. In this study, under hypoxic conditions (1% O~2~), we examined the effect of quercetin on the i