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Glucose intolerance following cis-platinum treatment in rats

✍ Scribed by Robin S. Goldstein; Gilbert H. Mayor; Robert W. Rosenbaum; Jerry B. Hook; Julio V. Santiago; Jenny T. Bond

Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
383 KB
Volume
24
Category
Article
ISSN
0300-483X

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The nephrotoxicity of cis-platinum (CDDP) in the rat can be controlled throughout a series of weekly administrations of CDDP (each of 5 mg kg-', i.v.) for at least three weeks by a combination of protective measures involving pretreatment with dithiocarbamates and diuretics and the administration of