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Glucose-dependency of the insulin stimulatory effect of glucagon-like peptide-1(7–36)amide on the rat pancreas

✍ Scribed by R Göke; B Wagner; HC Fehmann; B Göke

Book ID: 118399375
Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 74 KB
Volume: 40
Category: Article
ISSN: 0167-0115
DOI: 10.1016/0167-0115(92)90229-n

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## Background: The insulinotropic hormones, glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (7-36 amide) (glp-1), regulate insulin secretion to nutrient intake and constitute the endocrine arm of the entero-insular axis. glucagon has been implicated in the pathophysio