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Glucose biosensors based on thick film technology

✍ Scribed by U. Bilitewski; P. Rüger; R.D. Schmid

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
482 KB
Volume
6
Category
Article
ISSN
0956-5663

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✦ Synopsis

Various techniques for the fabrication of thick film biosensors are described. With electrodes printed on conventional thick film substrates, glucose is measured via the formation of hydrogen peroxide using glucose oxidase. Additional diffusion barriers extend the linear range of the sensor up to 15 mM. Using a new. flexible. untired substrate material sensors with a thteedimensional structure can be made. The resulting cavities can be tilled with carbon paste. Hence, the mediator technique and the use of dehydrogenases was applied to the fabrication of thick film biosensors. The linear range. sensitivity and stability of these sensors is strongly dependent on preparation methods such as the immobilization technique (mediated electrode) and the amount of cofactor and enzyme. Without any diffusion barrier the linear range is limited to about I mM for the sensor based on the dehydrogenase.

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